Endocrine Abstracts

Patients with chronic schizophrenia and psychosis are prone to develop hyponatremia secondary to psychogenic polydipsia. Hyponatremia secondary to water intoxication and its rapid correction are linked with rhabdomyolysis, an under-recognized yet serious condition. We report a case of 31 year old male with schizophrenia on Risperidone, who was brought to the emergency due to an unwitnessed fall and confusion. Serum sodium was 111 mmol/l, urine osmolality 55 mosm/kg and urine s...

Adrenal incidentalomas is a common referral to endocrine department. We retrospectively looked at the number of referrals to the endocrine services with it over 1 year and their eventual outcomes. There were a total of 37 patients referred with adrenal incidentalomas to our department out of which 28 patients (76%) were non secretory, while 1 (3%) had catecholamine excess. 1 (3%) had mixed cortisol + catecholamine excess. 7(19%) patients either did n...

Primary Hyperparathyroidism is one of the common endocrine disorders seen in an endocrine clinic. We retrospectively analysed patients referred with primary hyperparathyroidism over 1 yr (Oct 2013 - Sept 2014) and followed them over next 30 months. Patients with isolated secondary hyperparathyroidism were excluded. Few had secondary hyperparathyroidism in addition to primary hyperparathyroidism.50 patients with primary hyperparathy...

Adrenal incidentalomas is a common referral to endocrine department. We retrospectively looked at the number of referrals to the endocrine services with it over 1 year and their eventual outcomes. There were a total of 37 patients referred with adrenal incidentalomas to our department out of which 28 patients (76%) were non secretory, while 1 (3%) had catecholamine excess. 1 (3%) had mixed cortisol + catecholamine excess. 7(19%) patients either did n...

Primary Hyperparathyroidism is one of the common endocrine disorders seen in an endocrine clinic. We retrospectively analysed patients referred with primary hyperparathyroidism over 1 yr (Oct 2013 - Sept 2014) and followed them over next 30 months. Patients with isolated secondary hyperparathyroidism were excluded. Few had secondary hyperparathyroidism in addition to primary hyperparathyroidism.50 patients with primary hyperparathy...

Benign Ethnic Neutropenia (BEN) is a common form of neutropenia defined as an absolute blood neutrophil count (ANC) of < 1.5 x 109/l, usually observed in Afro-Caribbeans. These patients are not at increased risk of infection despite their neutropenia, unless they are on medications which can cause neutropenia. Amongst these drugs antithyroid medications are known to cause agranulocytosis defined as ANC of <500/μl. We report a case of 24 years old male w...

Background: Klinefelter syndrome (KS), karyotype 47XXY, affects 1 in 650 males. Subjects develop primary gonadal failure requiring life-long testosterone replacement. Many different testosterone formulations are available and long-term monitoring is necessary to avoid secondary polycythaemia.Objective: To investigate the effect of testosterone formulations used in KS subjects and estimate frequency of association with secondary polycythaemia.<p class...